Understanding PANS/PANDAS Triggers: Why Symptoms Flare
- Mel Mizrahie

- Jun 27
- 3 min read
Bonjour!
One of the things that makes PANS and PANDAS so confusing for families is that there isn't just one trigger.
Many parents first hear about PANDAS in relation to strep infections, and while strep is certainly one of the best-known triggers, it is only one piece of a much larger picture. Over time, many families notice that their child's symptoms worsen after a variety of illnesses. Sometimes they even flare after events that don't appear to be illnesses at all.
So why does this happen? it is not always a simple answer.
Infectious Triggers
PANDAS is specifically associated with Group A Streptococcal infections. PANS, however, has a much broader range of potential triggers.
These may include:
Group A Streptococcus (strep)
Mycoplasma pneumoniae
Tick-borne infections such as Lyme disease and Bartonella
Influenza
COVID-19
Epstein-Barr virus (EBV)
Ear and sinus infections
Many other viral or bacterial illnesses
For some children, even what seems like a simple cold can be enough to trigger a flare.

Beyond Infections
While infections are the best-known triggers, they are rarely the whole story.
Many factors can increase the overall burden on a child's immune system and nervous system, including:
Poor sleep
Emotional stress
School pressures or major life changes
Nutritional deficiencies
Blood sugar instability
Seasonal allergies
Mold exposure
Environmental toxins
Hormonal changes
Physical injuries or surgery
Digestive and gut health
When most people hear the word stress, they think about emotions. But from a biological perspective, stress is much broader than that. Stress is anything that forces the body to adapt.
Fighting an infection is stress.
Poor sleep is stress.
Mold exposure is stress.
Skipping meals or eating poorly can be stress.
Even growing, recovering from an injury, or going through hormonal changes places demands on the body.
The Bucket Analogy
I often ask parents to imagine their child's body as a bucket.
Every stressor adds a little more water.
A viral illness.
A few nights of poor sleep.
Seasonal allergies.
A stressful week at school.
Eventually, the bucket overflows.
That overflow is often what we recognize as a flare.
This also helps explain why the same trigger doesn't always produce the same response. A child may recover easily from one illness but experience a significant flare after another. It isn't always about the infection itself. Sometimes the body has simply reached its limit.
Looking Beyond the Trigger
This is one of the reasons I take a whole-child approach when working with families.
Of course I want to know what may have triggered a flare, but I also want to understand why this particular child is reacting this way.
Why does one child recover quickly while another develops weeks or months of symptoms?
Why does one sibling get strep without any lasting effects while another experiences a significant flare?
These are important questions.
A child's health history, temperament, sleep, digestion, immune resilience, environmental exposures, and individual pattern all provide valuable pieces of the puzzle.
How Can Homeopathy Help? How Can Homeopathy Help?
Classical homeopathy is highly individualized. Rather than treating a diagnosis alone, we select a remedy based on the unique characteristics of the child.
The goal isn't to calm the current flare. The goal is to support the body's ability to regulate and heal more effectively over time.
As overall health and resilience improve, many families report that their children recover more easily from illnesses, become less reactive to everyday stressors, and experience flares that are less frequent or less intense.
Homeopathy isn't about chasing one trigger after another. It's about helping the body become more resilient so it can respond to those triggers in a healthier way.
A Different Way of Looking at PANS/PANDAS
Children will always encounter germs. They'll have stressful weeks at school. They'll lose sleep, experience growth spurts, and face life's inevitable ups and downs. We can't remove every trigger, and we shouldn't expect to.
Instead, my goal is to help strengthen the child as a whole so their body is better able to respond to those challenges.
Every child with PANS or PANDAS has a unique story. That is why individualized care matters. Rather than focusing solely on the latest flare, I focus on understanding the child in front of me and supporting their long-term health, resilience, and recovery.
A votre santé!
Mel, The French Homeopath
Disclaimer: The articles on this website are provided for informational purposes only and are not intended as medical advice. Always consult with a qualified healthcare professional before making any changes to your health or treatment plan.




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